Polynucleotides fragments of purified DNA penetrate deep into the dermis activating fibroblasts and switching on the skin’s own regeneration pathways from within.
Anti-Wrinkle
Dermal Fillers
Amorim
PRP Therapy
Exosome Treatment
iS Clinical Facials
Microneedling
Fat Dissolving
Polynucleotides
Lumi Eyes
Vampire Facial
Fat Dissolving
Anti-Wrinkle
Dermal Fillers
Amorim
PRP Therapy
Exosome Treatment
iS Clinical Facials
Microneedling
Fat Dissolving
Polynucleotides
Lumi Eyes
Vampire Facial
Fat Dissolving
Polynucleotides commonly known by the active compound PDRN (Polydeoxyribonucleotide) are fragments of purified, highly biocompatible DNA derived from salmon or trout sperm. Before that raises any eyebrows the genetic material is so thoroughly processed and purified that the final product is simply a chain of nucleotide building blocks the same fundamental units that make up human DNA.
When injected into the skin these nucleotide chains are recognised by the body as repair signals. They bind to specific receptors on fibroblast cells triggering a cascade of regenerative activity: increased collagen and elastin synthesis enhanced hyaluronic acid production, and accelerated healing at a cellular level.
What makes polynucleotides uniquely remarkable is their ability to address the architecture of the skin itself not just its surface. They improve the quality and density of the extracellular matrix the invisible scaffolding that gives skin its firmness resilience and youthful structure. This is why results feel so genuine because they fundamentally are.
Victor has seen polynucleotide therapy transform skin that had stopped responding to conventional treatments. Used alone or as part of a wider regenerative protocol the results are consistent progressive and deeply rewarding for both practitioner and client.
PDRN directly activates fibroblasts your skin's structural repair cells promoting the production of new collagen and elastin to restore firmness and bounce.
One of the most effective treatments available for the periorbital area visibly improving dark circles, hollowness, crepiness, and fine lines around the eyes without filler.
Polynucleotides significantly boost the skin's own hyaluronic acid production delivering deep, lasting hydration and a luminosity that topical products cannot replicate.
Strongly anti-inflammatory by nature ideal for post-acne skin, rosacea, and reactive or sensitised skin types that have not responded well to other aesthetic treatments.
Post-Acne
Dull Complexion



Polynucleotides are still relatively new in the UK aesthetic market so we understand there are questions. Here are the ones Victor hears most often.
Victor will assess your skin, explain exactly which peel is right for you, and answer any questions without obligation or pressure.
Every polynucleotide session at Amorim Clinic is performed with the same unhurried care and clinical precision. You’ll never feel rushed and you’ll always leave knowing exactly what was done and what to expect next.
Victor begins with a detailed assessment of your skin discussing your concerns, reviewing your medical history, and examining the specific zones you're looking to address. He'll explain exactly how polynucleotides work and what a realistic treatment plan looks like for you, with zero obligation to proceed.
A prescription-strength numbing cream is applied to the treatment area and left for approximately 20 minutes. This ensures the injections are comfortable most clients describe the sensation as minimal pressure rather than pain. We never rush the numbing process; your comfort is non-negotiable.
Using a fine-gauge needle, Victor precisely microinjects the PDRN solution into the targeted areas including the delicate under-eye zone if appropriate. The injection pattern is carefully mapped to your anatomy to ensure even distribution and optimal depth. The treatment itself typically takes 20–30 minutes.
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